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Right CPA Epidermoid Cyst CaseNo: HN.1.1.1.1.001

Updated: May 7

Case Discussion CaseNo.HN.1.1.1.1.001




Clinical History : 15-year-old female presented with mild sensory changes on the right side of the face and intermittent dizziness.


Radiological Findings:  MRI: Right CPA lesion approximately 20 mm.


T1: Hypointense

Axial T1-weighted image showing a well-circumscribed, hypointense lesion in the right cerebellopontine angle, mildly compressing the brainstem
Axial T1-weighted image showing a well-circumscribed, hypointense lesion in the right cerebellopontine angle, mildly compressing the brainstem

T2: Hyperintense


Axial T2-weighted image demonstrating a hyperintense lesion with characteristic 'cauliflower' like appearance and thin internal septations
Axial T2-weighted image demonstrating a hyperintense lesion with characteristic 'cauliflower' like appearance and thin internal septations

Contrast-enhanced: No enhancement

Post-contrast axial T1-weighted image showing the non-enhancing nature of the lesion, distinguishing it from other CPA tumors
Post-contrast axial T1-weighted image showing the non-enhancing nature of the lesion, distinguishing it from other CPA tumors

Post-contrast sagittal T1-weighted image illustrating the craniocaudal extent of the cyst and its relationship with adjacent neural structures.
Post-contrast sagittal T1-weighted image illustrating the craniocaudal extent of the cyst and its relationship with adjacent neural structures.

DWI: Restricted diffusion

DWI provides the definitive diagnosis by showing hyperintensity, which is pathognomonic for epidermoid cysts compared to arachnoid cysts
DWI provides the definitive diagnosis by showing hyperintensity, which is pathognomonic for epidermoid cysts compared to arachnoid cysts


Diagnosis: Epidermoid cyst (confirmed by pathological examination)


Teaching Points: 


  • Epidermoid cysts contain keratin and slowly desquamating cellular debris; this dense, viscous content produces marked diffusion restriction on DWI.


  • This feature is key in differentiating them from arachnoid cysts, which typically do not restrict diffusion.


  • When combined with T1 hypointensity and T2 hyperintensity, diffusion restriction strongly suggests an epidermoid cyst even before pathology.


  • Lack of contrast enhancement and slow growth further support the benign nature of the lesion and help us differentiate it from other lesions such as meningiomas and schwannomas.


  • Surgical planning considers the lesion’s non-extension into the internal acoustic canal and relationship with neurovascular structures to minimize operative risk.


Video Presentation : Epidermoid Cyst (Right CPA)

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